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Coronavirus: Weak Point of Remdesivir
The drug Remdesivir only weakly inhibits the new coronavirus SARS-CoV-2. Research groups from Göttingen and Würzburg have discovered why this is so.
The Covid-19 drug Remdesivir (purple) is incorporated into the new RNA chain during the copying process and suppresses the duplication of the coronavirus genome. (Image: Hauke Hillen, Goran Kokic, Patrick Cramer / Max-Planck-Institut für biophysikalische Chemie Göttingen)
Remdesivir is the first drug against Covid-19 to be conditionally approved in Europe and the United States. The drug is designed to suppress the rapid replication of the SARS-CoV-2 virus in human cells by blocking the viral copying machine, called RNA polymerase.
New research has found that Vitamin D supplements will not protect from catching the common cold, flu, and other respiratory illnesses, ABC News reported.For the study, the researchers carried out a f
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How sure would you want to be that you have coeliac disease before starting a gluten-free diet
Biopsy of small bowel showing coeliac disease
A new survey from researchers at NIHR ARC West and the University of Bristol has been launched to understand how sure people want to be that they’ve got coeliac disease before starting a gluten-free diet.
Coeliac disease is when a person’s immune response to gluten attacks the tissues in their digestive system. This leads to damage in the gut, which makes it more difficult to absorb important nutrients from food. Around one in 100 people in the UK have coeliac disease, although many are not diagnosed. Untreated patients have an increased risk of anaemia, osteoporosis, cancer, or infertility. The only treatment available is a gluten-free diet.
Understanding mechanics behind cancer cell growth could improve diagnosis and treatment
Colon cancer cells in an aggregate embedded in a bioinert hydrogel
As cancer and tumor cells move inside the human body, they impart and are subject to mechanical forces. In order to understand how these actions affect cancer cell growth, spread, and invasion, a team of engineers at Rensselaer Polytechnic Institute is developing new models that mimic aspects of the mechanical environment within the body, providing new insight into how and why tumors develop in certain ways.
In research published today in Integrative Biology, a team of engineers from Rensselaer developed an in vitro – in the lab – lymphatic vessel model to study the growth of tumor emboli, collections of tumor cells within vessels that are often associated with increased metastasis and tumor recurrence.